Why would I need the HCV RNA Test?
This test is recommended for several reasons:
Confirmation of HCV infection: If you have tested positive for HCV antibodies, the HCV RNA test confirms if the infection is still active by detecting the presence of viral RNA.
Viral load measurement: To determine the amount of virus in your blood, which helps assess the severity of the infection and guide treatment decisions.
Monitoring treatment response: The HCV RNA test monitors the effectiveness of antiviral therapy in reducing the viral load in individuals undergoing treatment.
Post-treatment follow-up: To confirm that the virus has been eliminated from the bloodstream (known as sustained virologic response or SVR) after completing treatment.
What do the results of the HCV RNA Test indicate?
Detected (Positive) result:
Indicates an active HCV infection. The presence of HCV RNA in the blood confirms that the virus is replicating.
The viral load is also reported in international units per milliliter (IU/mL), indicating the amount of virus in the bloodstream.
Not detected (Negative) result:
Indicates that no HCV RNA was detected, which could mean:
The infection is inactive (e.g., a past infection that has been resolved or successfully treated).
The viral load is below the test's detection limit.
Further testing may be required if a recent exposure or infection is suspected.
What is the difference between Hepatitis C Virus (HCV) Antibody Test and Hepatitis C Virus (HCV) RNA Test?
The HCV Antibody Test is the first step in checking for exposure to hepatitis C. It indicates whether the immune system has ever encountered the virus but does not confirm whether the infection is active.
The HCV RNA Test is the follow-up test used to detect the actual virus and confirm whether there is an active infection. It also measures the viral load, helping to guide treatment decisions and monitor progress.
In conclusion, while the HCV Antibody Test is used for initial screening, the HCV RNA Test provides definitive information about the presence of an active infection and the viral load, making it critical for diagnosis and management.